Invited Presentations

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2022 • Back to top

            1. 286. The Importance of High Resolution Ion Mobility Mass Spectrometry to Accurately Read Back the Complex Language of Biology
              David C. Muddiman, Jeffrey Enders, Taufika Williams, & Kenneth P. Garrard
              Eastern Analytical Symposium, Plainsboro, NJ 2022
            2. 285. MSiReader Pro: An Intuitive and Innovative Vender Neutral Software for Mass Spectrometry Imaging
              Alena N. Joignant & David C. Muddiman
              Pre-Meeting Workshop, IMSS, Baltimore, MD 2022
            3. 284. From LC-MS and LC-HRIM-MS Glycomics to Mass Spectrometry Imaging: Novel Chemistry and Platform Technologies with Diverse Applications in Human Health and Disease
              David C. Muddiman
              ACS Fall Conference, Chicago, IL 2022
            4. 283. Novel 2D and 3D Mass Spectrometry Imaging by IR-MALDESI: From Understanding Cancer and Xenobiotic Metabolism to Wound Healing
              David C. Muddiman
              Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 2022
            5. 282. NextGen IR-MALDESI Mass Spectrometry Imaging: Instrument Development and Recent Applications
              David C. Muddiman
              ACS Spring Conference, San Diego, CA 2022
            6. 281. Statistical Approach for System Suitability Testing (SST) for Mass Spectrometry Imaging using IR-MALDESI
              David C. Muddiman
              18th Annual Meeting of the US Human Proteome Organization, Charleston, SC 2022

          2021Back to top

                  1. 280. Determination of the Inter-Variability of N-Linked Glycans in Human Frontal Cortex Brain Tissue: From Optimized INLIGHT Chemical Labeling to Ion-Mobility MS
                    David C. Muddiman
                    The International Chemical Congress of Pacific Basin Societies 2022
                  2. 279. New Directions in IR-MALDESI Mass Spectrometry Imaging: From Cells, Bones and Neurotransmitters to Drift Tube Ion Mobility
                    David C. Muddiman
                    The International Chemical Congress of Pacific Basin Societies 2021
                  3. 278. Quantifying Human Exposure to Emerging Contaminants of Concern using Mass Spectrometry
                    David C. Muddiman
                    Isotope Day, Cambridge Isotope Laboratories, Tewsbury, MA 2021
                  4. 277. Scientific Discovery and Impact Through Innovative Mass Spectrometry Measurements: From Plants and Model Organisms to Humans
                    David C. Muddiman
                    Department of Chemistry, George Washington University, Washington, DC 2021
                  5. 276. Scientific Discovery and Impact Through Innovative Mass Spectrometry Measurements: From Plants and Model Organisms to Humans
                    David C. Muddiman
                    Central Ohio Mass Spectrometry Discussion Group, Columbus, OH  2021
                  6. 275. Scientific Discovery and Impact through Innovative Mass Spectrometry Measurements: From Plants and Model Organisms to Humans
                    David C. Muddiman
                    Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 2021

                2020Back to top

                        1. 274. New Directions for IR-MALDESI Mass Spectrometry Imaging: From Cells and Bones to Drift Tube Ion Mobility
                          David C. Muddiman and Erin S. Baker
                          Mass Spectrometry Applications to the Clinical Laboratory, Palm Springs, CA 2020
                        2. 273. New Directions for IR-MALDESI Mass Spectrometry Imaging: From Cells, Bones and Neurotransmitters to Drift Tube Ion Mobility
                          David C. Muddiman and Erin S. Baker
                          United States Human Proteome Organization, Seattle, WA 2020
                        3. 272. Scientific Discovery and Impact Through Innovative Mass Spectrometry Measurements: From Plants and Model Organisms to Humans
                          David C. Muddiman
                          Thermo Fisher Scientific Global Sales Meeting, San Antonio, TX  2020
                        4. 271. Unraveling Chemical and Biological Systems Through the Development and Application of Innovative Mass Spectrometry Platform Technologies
                          David C. Muddiman
                          Department of Marine, Earth and Atmospheric Sciences, NC State University, Raleigh, NC 2020

                      2019Back to top

                              1. 270. IR-MALDESI Coupled with Ion Mobility: Early Results
                                David C. Muddiman
                                1st Annual North American Ion Mobility User Meeting, Alumni Center, NC State University, Raleigh, NC 2019
                              2. 269. High Throughput Screening by Adaptation of IR-MALDESI-MS
                                David C. Muddiman
                                Southeastern Regional Meeting of the American Chemical Society, Savannah, GA 2019
                              3. 268. Infrared Matrix-Assited Laser Desorption Electrospray Ionization (IR-MALDESI): From Fundamentals to New Directions
                                David C. Muddiman
                                Agilent Technologies, Santa Clara, CA 2019
                              4. 267. Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI) as a Novel Platform for Molecular Microscopy
                                David C. Muddiman
                                Asilomar Meeting on Mass Spectrometry, Pacific Grove, CA 2019
                              5. 266. Innovations in Chemistry and Mass Spectrometry Platform Technologies and Their Application to Diverse Biological Problems
                                David C. Muddiman
                                Seton Hall University, South Orange, NJ 2019
                              6. 265. Innovations in Chemistry and Mass Spectrometry Platform Technologies and Their Application to Diverse Biological Problems
                                David C. Muddiman
                                University of British Columbia, Vancover, Canada 2019
                              7. 264. Innovations in Chemistry and Mass Spectrometry Platform Technologies and Their Application to Diverse Biological Problems
                                David C. Muddiman
                                The European Molecular Biology Laboratory, Heidleberg, Germany 2019
                              8. 263. Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI): Background, Potential, and Limitations
                                David C. Muddiman
                                Abbvie Inc, Chicago, IL 2019
                              9. 262. Innovations in Chemistry and Mass Spectrometry Platform Technologies and Their Application to Diverse Biological Problems
                                David C. Muddiman
                                Department of Biochemistry, NC State University, Raleigh, NC 2019
                              10. 261. Innovations in Chemistry and Mass Spectrometry Platform Technologies and Their Application to Diverse Biological Problems
                                David C. Muddiman
                                Brigham Young University, Provo, UT 2019
                              11. 260. Innovations in Chemistry and Mass Spectrometry Platform Technologies for Quantitative Glycomics
                                David C. Muddiman, Jaclyn Gowen, James Dodds, Erin S. Baker, Daniel M. Rotroff, James N. Petitte, Alison A. Motsinger-Reif, Michael MacCoss, Thomas Montine
                                15th Annual Conference of the United States Human Proteome Organization: Proteomics at the Frontier of Biology and Medicine, Rockville, MD 2019

                      2018Back to top

                              1. 259. New Advances in IR-MALDESI for Mass Spectrometry Imaging
                                David C. Muddiman
                                IMSS II and OurCon VI, Charleston, SC 2018
                              2. 258. Innovations in Chemistry and Mass Spectrometry Platform Technologies for SystemsLevel Measurements
                                David C. Muddiman
                                Thermo Fisher Scientific, San Jose, CA 2018
                              3. 257. Innovations in Chemistry and Mass Spectrometry Platform Technologies for
                                Quantitative Glycomics
                                David C. Muddiman
                                Understanding the Role of Glycosylation in Alzheimer’s Disease, Division of
                                Neuroscience, National Institute on Aging, Bethesda, Maryland 2018
                              4. 256. Innovations in Chemistry and Mass Spectrometry Platform Technologies for SystemsLevel Measurements
                                David C. Muddiman
                                Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North
                                Carolina State University 2018
                              5. 255. Innovations in Mass Spectrometry Platform Technologies to Address Diverse Biological
                                Research Hypotheses
                                David C. Muddiman
                                James Madison University, Harrisonburg, VA 2018
                              6. 254. Development and Application of IR-MALDESI for 2D and 3D Imaging
                                David C. Muddiman
                                The Pittsburgh Conference, Orlando, FL 2018
                              7. 253. Development of INLIGHT for Quantiative Glycomics
                                David C. Muddiman
                                The Pittsburgh Conference, Orlando, FL 2018
                              8. 252. IR MALDESI: from Technological Innovations to Cancer, HIV Treatment and Exposomics
                                David C. Muddiman
                                Mass Spectrometry Applications to the Clinical Laboratory, Palm Springs, CA 2018
                              9. 251. Innovations in Mass Spectrometry Platform Technologies for Epithelial Ovarian Cancer Research and High Throughput Screenings
                                David C. Muddiman
                                Washington Chromatography Discussion Group, Rockville, MD 2018

                      2017Back to top

                              1. 250. IR-MALDESI: An Innovative Approach to Molecular Microscopy
                                David C. Muddiman
                                Temple University, Philadelphia, PA 2017
                              2. 249. IR-MALDESI: An Innovative Mass Spectrometry Imaging Platform Technology
                                David C. Muddiman
                                SERMACS, Charlotte, NC 2017
                              3. 248. IR-MALDESI: An Innovation Approach to Molecular Microscopy
                                David C. Muddiman
                                NIEHS, Research Triangle Park, NC 2017
                              4. 247. Innovative Mass Spectrometry Chemistries and Technologies to Read the Complex Language of Biology
                                David C. Muddiman
                                East China Normal University, Shanghai, China 2017
                              5. 246. Innovative Mass Spectrometry Chemistries and Technologies to Read the Complex Language of Biology
                                David C. Muddiman
                                Dalian Institute of Chemical Physics, Dalian, China 2017
                              6. 245. Novel Discoveries in Ovarian Cancer and ALS: From Proteome Profiling to Proteoforms
                                David C. Muddiman
                                Stockholm University, Stockholm, Sweden in November 2017
                              7. 244. Innovative Mass Spectrometry Approaches to Unravel Biology
                                David C. Muddiman
                                Department of Plant and Microbial Biology, NC State University 2017
                              8. 243. Novel Discoveries in Ovarian Cancer and ALS: From Proteome Profiling to Proteoforms
                                David C. Muddiman
                                Montreal Mass Spectrometry Discussion Group, Montreal, Canada 2017
                              9. 242. Chemical and Mass Spectrometry Strategies Enabling Human Health Biological Discoveries
                                David C. Muddiman
                                Cambridge Isotope Laboratories, Tewksbury, MA 2017
                              10. 241. Elucidation of Novel Proteoforms of Superoxide Dismutase (SOD1) in Sporadic ALS Patients
                                David C. Muddiman
                                United States Human Proteome Organization, San Diego, CA 2017
                              11. 240. Novel Discoveries in Ovarian Cancer and ALS: From Proteome Profiling to Proteoforms
                                David C. Muddiman
                                OMICS Strategies to Study the Proteome, Breckenridge, CO 2017

                      2016Back to top

                              1. 239. Elucidation of Novel Proteoforms of Superoxide Dismutase (SOD1) in Sporadic ALS Patients
                                David C. Muddiman
                                Thermo Fisher Scientific Seminar Series, Bethesda, MD 2016
                              2. 238. Innovative Chemistries and Technologies to Read the Complex Language of Biology
                                David C. Muddiman
                                Washington-Baltimore Mass Spectrometry Discussion Group, Vendor Night, Columbia, MD 2016
                              3. 237. TransOMICS: From Innovative Technology and Model Organisms to Biological Impact
                                David C. Muddiman
                                Department of Molecular Science and BioDesign Institute, Arizona State University, Tempe, AZ 2016
                              4. 236. IR-MALDESI Mass Spectrometry Imaging of Complex Chemical and Biological Systems
                                David C. Muddiman
                                252nd National American Chemical Society Meeting and Exposition, Philadelphia, PA 2016
                              5. 235. TransOMICS: Integration of IR-MALDESI MSI with LMD Proteomics Data
                                David C. Muddiman
                                International Mass Spectrometry Conference, Toronto, Canada 2016
                              6. 234. IR MALDESI: A Novel Molecular Microscopy Method to Determine Drug Distributions in Tissues
                                David C. Muddiman
                                Analytica 2016, Munich, Germany 2016
                              7. 233. IR-MALDESI: An Innovative Approach to Molecular Microscopy
                                David C. Muddiman
                                Mass Spectrometry Applications to the Clinical Laboratory, Palm Springs, CA 2016
                              8. 232. IR-MALDESI: An Innovation Approach to Molecular Microscopy
                                David C. Muddiman
                                Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 2016

                      2015Back to top

                              1. 231. Working Around the Cluck: A Systems Biology Approach to Understand the Origin and Biology of Ovarian Cancer
                                David C. Muddiman
                                Cancer Center, University of Arkansas, Little Rock, AR 2015
                              2. 230. Innovative Molecular Analysis Technologies to Unravel Complex Biological Questions,
                                David C. Muddiman
                                Central North Carolina American Chemical Society, Syngenta, Greensboro, NC 2015
                              3. 229. Working Around the Cluck: A Systems Biology Approach to Understand the Origin and Biology of Ovarian Cancer
                                David C. Muddiman
                                Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill,
                                Chapel Hill, NC
                                2015
                              4. 228. Innovative Molecular Analysis Technologies to Unravel Complex Biological Questions,
                                David C. Muddiman
                                Department of Chemistry, Iowa State University, Ames, IA 2015
                              5. 227. Working Around the Cluck: A Systems Biology Approach to Understand the Origin and Biology of Ovarian Cancer
                                David C. Muddiman
                                Institute for Systems Biology, Seattle, WA 2015
                              6. 226. Innovative Molecular Analysis Technologies to Unravel Complex Biological Systems
                                David C. Muddiman
                                Bay Area Mass Spectrometry Discussion Group, Foster City, CA 2015
                              7. 225. The Importance of Ultrahigh Specificity in Reading the Complex Language of Biology
                                David C. Muddiman
                                The Pittsburgh Conference, New Orleans, LA 2015
                              8. 224. The Importance of Ultrahigh Specificity in Reading the Complex Language of Biology
                                David C. Muddiman
                                United States Human Proteome Organization, Tempe, AZ 2015

                      2014Back to top

                              1. 223. Discovery of N-Linked Glycan Biomarkers in Domestic Hen Model of Ovarian Cancer using INLIGHT™ Strategy
                                David C. Muddiman
                                6th Annual Meeting of the Proteomics Society, India Institute of Technology, Mumbai, India, 2014
                              2. 222. Quantitative Mass Spectrometry Imaging (QMSI) by a Novel IR-MALDESI Approach
                                David C. Muddiman
                                6th Annual Meeting of the Proteomics Society, India Institute of Technology, Mumbai, India, 2014
                              3. 221. Mapping HIV Drug Distributions using a Novel Mass Spectrometry Imaging Source
                                David C. Muddiman
                                American Association for Pharmaceutical Sciences, San Diego, CA 2014
                              4. 220. Development of a Novel Atmospheric Pressure Ionization Source for Biological and Chemical Imaging
                                David C. Muddiman
                                SERMACS, Nashville, TN 2014
                              5. 219. Quantitatively Controlling Chaos: The N-Linked Glycome of an Integrated Systems Biology Approach to Understanding Ovarian Cancer Initiation and Progression
                                David C. Muddiman
                                Asilomar Conference, Advances in Glycomics and Glycoproteomics: Methods and Applications, Pacific Grove, CA 2014
                              6. 218. Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI): From Fundamentals to Tissue and Chemical Imaging
                                David C. Muddiman
                                248th ACS National Meeting, San Francisco, CA 2014
                              7. 217. Quantitatively Controlling Chaos: Adventures in Absolute Protein Quantification
                                David C. Muddiman
                                Cold Spring Harbor Laboratory, Long Island, NY 2014
                              8. 216. Thing 1 and Thing 2 (and Thing 3): ESI, MALDI and Hybrids of the Two
                                David C. Muddiman
                                Cold Spring Harbor Laboratory, Long Island, NY 2014
                              9. 215. Mapping HIV Drugs in Tissue using IR-MALDESI MSI Coupled to the Q-Exactive with Several Acquisition Modes
                                David C. Muddiman, Jeremy A. Barry, Guillaume Robichaud, Mark Bokhart, Elias Rosen, Milad Nazari, Troy Ghashghaei, Corbin Thompson, Craig Sykes, and Angela Kashuba
                                62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, MD 2014
                              10. 214. Development of the INLIGHT™ Strategy for the Relative Quantification of N-Linked Glycans using Different Separation Modes
                                David C. Muddiman, Amber C. Cook, James P. McCord, Liangliang Sun, Norman J. Dovichi
                                HPLC 2014, New Orleans, LA 2014
                              11. 213. Quantitatively Controlling Chaos: The New Biology
                                David C. Muddiman
                                Triangle Area Mass Spectrometry Discussion Group, Genome Sciences, UNC Chapel Hill 2014
                              12. 212. Infrared MALDESI Imaging Source Coupled to Q-Exactive for Discovery-Based and Targeted Analysis of Endogenous and Exogenous Species in Tissues
                                David C. Muddiman
                                Frontiers in Instrumentation, 10th Annual United States Human Proteome Organization, Seattle, WA 2014
                              13. 211. Quantitative and Comprehensive Chemistry and Technology: THE NEW BIOLOGY
                                David C. Muddiman
                                Arizona Mass Spectrometry Discussion Group, Tucson, AZ 2014
                              14. 210. Development of the INLIGHT™ Strategy for the Relative Quantification of N-Linked Glycans in Complex Biospecimens
                                David C. Muddiman
                                The Pittsburgh Conference, Chicago, IL 2014
                              15. 209. Quantitative and Comprehensive Chemistry and Technology: THE NEW BIOLOGY
                                David C. Muddiman
                                Eastern Virginia Medical School, Norfolk, VA 2014
                              16. 208. Innovative Chemical and Instrumental Approaches Directed at Unraveling Complex Biological Systems
                                David C. Muddiman
                                Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC 2014
                              17. 207. Innovative Chemical and Instrumental Approaches Directed at Unraveling Complex Biological Systems
                                David C. Muddiman
                                Department of Chemistry, University of Alberta, Edmonton, AL 2014

                      2013Back to top

                              1. 206. Development of Novel Chemical and Instrumental Methods using Design of Experiments for Quantitative Proteomic, Glycomic, Metabolomic, and Lipidomic Measurements in Complex Biological Systems
                                David C. Muddiman
                                Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 2013
                              2. 205. Development and Application of the INLIGHT Relative Quantification Strategy: From Monitoring Glycostasis to Early Detection of Ovarian Cancer
                                David C. Muddiman
                                Boston Glycobiology Discussion Group, Boston University Medical Campus, Boston, MA 2013
                              3. 204. Fundamentals and Applications of Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Source for Mass Spectrometry Imaging
                                David C. Muddiman
                                246th ACS National Meeting, Indianapolis, IN 2013
                              4. 203. Individuality Normalization and Labeling with Isotopic Glycan Hydrazide Tags (INLIGHT): A Novel Glycan Relative Quantification Strategy, Development and Application
                                David C. Muddiman, S. Hunter Walker, Amber C. Cook, Amber D. Taylor
                                Cold Spring Harbor Laboratory, Long Island, NY 2013
                              5. 202. Mass Spectrometry-Based Absolute Protein Quantification
                                David C. Muddiman and Philip L. Loziuk
                                Cold Spring Harbor Laboratory, Long Island, NY 2013
                              6. 201. Electrospray Ionization, Matrix-Assisted Laser Desorption Ionization, and Hybrid of the Two: From Mechanisms to Imaging
                                David C. Muddiman, Jeremy A. Barry, and Guillaume Robichaud
                                Cold Spring Harbor Laboratory, Long Island, NY 2013
                              7. 200. Proteolysis and Peptide Decay: Considerations for Discovery and Targeted Proteomic Workflows with Applications to Systems Modeling of Lignin and Cellulose Biosynthesis
                                David C. Muddiman and Philip L. Loziuk
                                American Society for Mass Spectrometry, Minneapolis, MN 2013
                              8. 199. Innovations and Findings in Academic Research: Translating them to the Pharmaceutical Industry
                                David C. Muddiman
                                GlaxoSmithKline, Worldwide VTC, RTP, NC 2013

                      2012Back to top

                              1. 198. N-Linked Glycan Hydrophobic Tagging, Profiling, and Relative Quantification Strategy Toward Biomarker Discovery Efforts in the Hen Model of Spontaneous Ovarian Cancer
                                David C. Muddiman
                                National Institutes of Health, Innovative Molecular Analysis Technologies Meeting, Houston, TX 2012
                              2. 197. Chemical and Synthetic Biology Approaches for Polyketide Diversification
                                G. Williams, J. McArthus, S. Randall, M. Draelos, E.M. Musiol, Z. Ye, C. Ladner, D.C. Muddiman, T. Weber
                                Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC 2012
                              3. 196. Ambient Tissue Imaging using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry
                                David C. Muddiman
                                Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC 2012
                              4. 195. New Chemical and Instrumental Tools for Quantitatively Exploring the N-Linked Glycome
                                David C. Muddiman
                                Boston Glycobiology Discussion Group, Boston, MA 2012
                              5. 194. Development of Novel Chemical and Instrumental Methods using Design of Experiments for Quantitative Proteomic Measurements in Complex Biological Systems
                                David C. Muddiman
                                Department of Chemistry, Brandeis University, Boston, MA 2012
                              6. 193. N-linked Glycan Profiling Strategy Toward Biomarker Discovery Efforts in the Hen Model of Spontaneous Ovarian Cancer
                                David C. Muddiman and S. Hunter Walker
                                4th Charles Warren Workshop, CCRC, University of Georgia, Athens, GA 2012
                              7. 192. MALDI, ESI and Hybrids of the Two
                                David C. Muddiman, Jeremy A. Barry, and Guillaume Robichaud
                                Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 2012
                              8. 191. Mass Spectrometry-based Absolute Protein Quantification
                                David C. Muddiman and Christopher M. Shuford
                                Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 2012
                              9. 190. The Impact of Fourier Transform Mass Spectrometry on Biological Research
                                David C. Muddiman
                                The Pittsburgh Conference, Orlando, FL 2012 (Award Symposium Honoring Alan Marshall)
                              10. 189. Proteomics and Glycomics Tools for the Study of Human Disease
                                David C. Muddiman
                                GlaxoSmithKline, King of Prussia, PA 2012
                              11. 188. N-Linked Glycan Hydrophobic Tagging, Profiling, and Relative Quantification Strategy Toward Biomarker Discovery Efforts in the Hen Model of Spontaneous Ovarian Cancer
                                David C. Muddiman
                                National Institutes of Health, Innovative Molecular Analysis Technologies Meeting, Houston, TX 2012
                              12. 187. Chemical and Synthetic Biology Approaches for Polyketide Diversification
                                G. Williams, J. McArthus, S. Randall, M. Draelos, E.M. Musiol, Z. Ye, C. Ladner, D.C. Muddiman, T. Weber
                                Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC 2012
                              13. 186. Ambient Tissue Imaging using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Mass Spectrometry
                                David C. Muddiman
                                Southeastern Regional Meeting of the American Chemical Society, Raleigh, NC 2012
                              14. 185. New Chemical and Instrumental Tools for Quantitatively Exploring the N-Linked Glycome
                                David C. Muddiman
                                Boston Glycobiology Discussion Group, Boston, MA 2012
                              15. 184. Development of Novel Chemical and Instrumental Methods using Design of Experiments for Quantitative Proteomic Measurements in Complex Biological Systems
                                David C. Muddiman
                                Department of Chemistry, Brandeis University, Boston, MA 2012
                              16. 183. N-linked Glycan Profiling Strategy Toward Biomarker Discovery Efforts in the Hen Model of Spontaneous Ovarian Cancer
                                David C. Muddiman and S. Hunter Walker
                                4th Charles Warren Workshop, CCRC, University of Georgia, Athens, GA 2012
                              17. 182. MALDI, ESI and Hybrids of the Two
                                David C. Muddiman, Jeremy A. Barry, and Guillaume Robichaud
                                Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 2012
                              18. 181. Mass Spectrometry-based Absolute Protein Quantification
                                David C. Muddiman and Christopher M. Shuford
                                Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 2012
                              19. 180. The Impact of Fourier Transform Mass Spectrometry on Biological Research
                                David C. Muddiman
                                The Pittsburgh Conference, Orlando, FL 2012 (Award Symposium Honoring Alan Marshall)
                              20. 179. Proteomics and Glycomics Tools for the Study of Human Disease
                                David C. Muddiman
                                GlaxoSmithKline, King of Prussia, PA 2012

                      2011Back to top

                              1. 178. Novel Reagents to Probe the N-Linked Glycome for the Study of Spontaneous EOC in the Chicken Model
                                David C. Muddiman
                                Innovative Molecular Analysis Technologies, National Cancer Institute, Bethesda, MD 2011
                              2. 177. New Chemical and Instrumental Tools for Exploring the Proteome and Glycome
                                David C. Muddiman
                                Department of Chemistry, Brown University, Providence, RI 2011
                              3. 176. From Innovative Technologies to Model Organisms: The Search for Biomarkers for the Detection of Early Stage Epithelial Ovarian Cancer
                                David C. Muddiman
                                UW- Madison Human Proteomics Symposium, Madison, WI 2011
                              4. 175. Characterization of the UV- and IR-Matrix-Assisted Laser Desorption Ionization (MALDESI) Source with Integrated RASTIR
                                MARM of the American Chemical Society, College Park, MD 2011
                              5. 174. Innovative Approaches to Proteomics and Glycomics Research
                                David C. Muddiman
                                Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 2011
                              6. 173. Intra- and Inter-Individual Variability of Plasma Proteins in the Chicken Model of Spontaneous Epithelial Ovarian Cancer via Selected Reaction Monitoring
                                Adam Hawkridge; Genna Andrews; James Petitte; David C. Muddiman
                                7th Annual United State Human Proteome Organization Meeting, Raleigh, NC 2011
                              7. 172. Innovative Approaches to Proteomics and Glycomics Research
                                David C. Muddiman
                                Department of Chemistry and Biochemistry, University of North Carolina-Greensboro, North Carolina 2011
                              8. 171. Innovation and Application of Proteomics and Glycomics Strategies Directed at Epithelial Ovarian Cancer
                                David C. Muddiman
                                The Scripps Research Institute, Jupiter, Florida, 2011

                      2010Back to top

                              1. 170. Development of Novel Strategies for Proteomics and Glycomics Research
                                David C. Muddiman
                                Eastern Analytical Symposium Honoring Richard D. Smith, 2010 EAS Awardee for Outstanding Achievements in the Fields of Analytical Chemistry, East Somerset, New Jersey,
                                2010
                              2. 169. Matrix-Assisted Laser Desorption Electrospray Ionization: Mechanisms, Technology, and Application
                                David C. Muddiman
                                26th Asilomar Conference on Mass Spectrometry, Pacific Grove, CA, 2010
                              3. 168. Development and Application of Mass Spectrometry-Based Biomarker Discovery Technologies for the Early Detection of Epithelial Ovarian Cancer
                                David C. Muddiman
                                The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2010
                              4. 167. Development and Application of Mass Spectrometry-Based Biomarker Discovery Technologies for the Early Detection of Epithelial Ovarian Cancer
                                David C. Muddiman
                                Texas A&M; University, College Station, TX, 2010
                              5. 166. Matrix-Assisted Laser Desorption Electrospray Ionization (MALDESI)
                                David C. Muddiman
                                Precision Engineering Center, Monteith Engineering Research Center, North Carolina State University, Raleigh, NC, 2010
                              6. 165. New Ionization Methods for Large-Molecule Top-Down Mass Spectrometry
                                David C. Muddiman
                                United States Human Proteome Organization, Denver, CO, 2010
                              7. 164. Proteomics and Glycomics Approaches to Elucidate Biomarkers for the Early Detection of Ovarian Cancer
                                David C. Muddiman
                                PittCon 2010, Orlando, Florida, 2010

                      2009Back to top

                              1. 163. Development and Application of Chemical and Instrumental Approaches Directed at Biomarker Discovery
                                David C. Muddiman
                                Department of Chemistry, Louisiana State University, Baton Rouge, LA, 2009
                              2. 162. Development and Application of Chemical and Instrumental Approaches Directed at Biomarker Discovery
                                David C. Muddiman
                                Department of Chemistry, George Washington University, Washington, DC, 2009
                              3. 161. Developing Novel Hybrid Ionization Sources Around the MALDESI Technology Platform
                                Adam M. Hawkridge and David C. Muddiman
                                Federation of Analytical Chemistry and Spectroscopy Societies, Louisville, KY, 2009
                              4. 160. Mass Spectrometry-Based Biomarker Discovery: Towards a Global Proteome Index-of-Individuality
                                David C. Muddiman and Adam M. Hawkridge
                                Pharmaceutical and Biomedical Analysis, Orlando, FL, 2009
                              5. 159. The Development of an Aerodynamic Focusing Device, the Air Amplifier, for Improved Biomarker Analyses by Mass Spectrometry
                                David C. Muddiman, R. Brent Dixon, Amarnatha S. Potturi, Dan Cassidy, Jack R. Edwards, Alex Sohn, Guillaume Robichaud, Thomas A. Dow
                                NCI IMAT Grantee Meeting, Bethesda, MD, 2009
                              6. 158. Rationale Ovarian Cancer Biomarker Discovery: The Importance of Longitudinal Experimental Designs
                                David C. Muddiman
                                ADAPT Congress, Washington, DC, 2009
                              7. 157. Cancer Biomarker Discovery and Quantification using Mass Spectrometry
                                David C. Muddiman
                                Precision Engineering Center, Monteith Engineering Research Center, North Carolina State University, Raleigh, NC, 2009
                              8. 156. Development and Application of Chemical and Instrumental Approaches Directed at Biomarker Discovery
                                David C. Muddiman
                                Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC, 2009
                              9. 155. Ambient Ionization Methods Coupled to FTMS for Direct Analysis and Imaging Applications
                                David C. Muddiman
                                Center for Analytical and Instrumentation Development, Purdue University, West Lafayette, IN, 2009
                              10. 154. Development of Atmospheric Pressure Ionization Sources Coupled to FT-ICR Mass Spectrometry for the Characterization of Biological Molecules
                                David C. Muddiman, Jason S. Sampson, K.K. Murray, R.B. Dixon
                                7th North American FT MS Conference, Key West, FL, 2009
                              11. 153. Development and Application of FT-ICR Mass Spectrometry for Proteomics and Glycomics Research
                                BASF, The Chemical Company, Research Triangle Park, NC, 2009
                              12. 152. Aligning Chemistry and High End Mass Spectrometry with Important Clinical Problems: Building a Strong Foundation Based on Interdisciplinary Collaborations
                                David C. Muddiman
                                Department of Chemistry, UNC Chapel Hill, Chapel Hill, NC, 2009
                              13. 151. Integration of Engineering, Chemistry, and Medicine: Progress Towards the Molecular Characterization of Cancer
                                David C. Muddiman
                                Department of Chemistry, NC A & T University, Greensboro, NC, 2009

                      2008Back to top

                              1. 150. Innovative Ionization Sources for Imaging Mass Spectrometry
                                David C. Muddiman
                                Department of Chemistry, Georgia Institute of Technology, Atlanta, GA, 2008
                              2. 149. A Combinatorial Approach: The Use of MALDI-MS and Nano LC-MS for Glycan Biomarker Discovery
                                David C. Muddiman
                                Diosynth Biotechnology, Cary, NC, 2008
                              3. 148. New Ionization Sources for Biological Mass Spectrometry
                                David C. Muddiman
                                Asilomar Conference on Mass Spectrometry, New Methods, Instrumentation, and Applications of Ion Traps, Pacific Grove, CA, 2008
                              4. 147. Time-of-Flight Mass Analyzers: Single-Ion Counting versus ADC Detection
                                David C. Muddiman
                                US LC/MS Innovations Seminar Tour, Agilent Technologies, Durham, NC, 2008
                              5. 146. Innovative Technology Development Directed at the Elucidation of Biomarkers for the Detection of Early-State Ovarian Cancer
                                Taufika I. Williams, Michael S. Bereman, D. Keith Williams, Kimberly K. Kalli, William A. Cliby and David C. Muddiman
                                National Cancer Institute, Innovative Molecular Analysis Technologies, Cambridge, MA, 2008
                              6. 145. A Combinatorial Approach: The Use of MALDI-MS and Nano LC-MS for Glycan Biomarker Discovery
                                Taufika Islam Williams, Michael S. Bereman, Kimberly A. Kalli, William A. Cliby and David C. Muddiman
                                Sixth Annual Protein Biomarkers Conference, Philadelphia, PA, 2008
                              7. 144. Driving Research with a Multidisciplinary Approach
                                David C. Muddiman
                                Bioinformatics and Bioengineering Summer Institute, Virginia Commonwealth University, Richmond, VA, 2008
                              8. 143. Glycan Profiling in Plasma: Fundamentals and Applications to Ovarian Cancer
                                Taufika Islam Williams and David C. Muddiman
                                The Pittsburgh Conference, New Orleans, LA, 2008

                      2007Back to top

                              1. 142. Mass Spectrometry Detection Techniques Available for Qualitative and Quantitative Assays – Small vs. Large Molecules
                                David C. Muddiman
                                American Association of Pharmaceutical Scientists, San Diego, CA, 2007
                              2. 141. Fundamentals and Applications of DESI and MALDESI Coupled to FT-ICR-MS
                                David C. Muddiman
                                Workshop on The Art of Open Air Ionization on Surfaces, Philadelphia, PA, November 8-9, 2007
                              3. 140. Plasma Biomarker Discovery and Analysis using FT-ICR Mass Spectrometry
                                David C. Muddiman, Adam Hawkridge, Taufika I. Williams, William Cliby, and John Burnett
                                Federation of Analytical Chemistry and Spectroscopy Societies Memphis, TN, 2007
                              4. 139. Development of Hybrid Atmospheric Ionization Sources for Direct Analysis of Macromolecules by FT-ICR-MS
                                David C. Muddiman, Adam Hawkridge, Jason S. Sampson, Michael S. Bereman and R. Brent Dixon
                                Federation of Analytical Chemistry and Spectroscopy Societies Memphis, TN, 2007
                              5. 138. New Mass Spectrometric Proteomic Technologies
                                David C. Muddiman
                                Metabolomics and Proteomics Seminar Series, Department of Biochemistry, University of Minnesota, St. Paul, MN, 2007
                              6. 137. Advancing Quantitative Proteomics Technologies
                                David C. Muddiman
                                Minnesota Mass Spectrometry Discussion Group, Minneapolis, MN, 2007
                              7. 136. Chemical and Mass Spectrometry Advances for Improved Clinical Proteomic Measurements David C. Muddiman
                                Department of Chemistry, University of Michigan, Ann Arbor, MI, 2007
                              8. 135. nanoRP-HPLC and SCX-nanoRP-HPLC coupled to FT-ICR Mass Spectrometry to Effectively Address Complex Biological Mixtures
                                David C. Muddiman
                                Triangle Chromatography Discussion Group Symposium, Raleigh, NC, 2007
                              9. 134. Statistical Issues in Mass Spectrometry Based Proteomics
                                David C. Muddiman
                                Department of Statistics, North Carolina State University, Raleigh, NC, 2007
                              10. 133. Innovations and Applications of the LTQ-FT in the Biological Arena
                                David C. Muddiman
                                ThermoElectron Users Meeting, Cincinnati, OH, 2007
                              11. 132. Innovations and Applications of the LTQ-FT in the Biological Arena
                                David C. Muddiman
                                ThermoElectron Users Meeting, Chicago, IL, 2007
                              12. 131. Novel Chemical and Instrumental Approaches to Effectively Address Clinical Proteomic Problems
                                David C. Muddiman
                                Department of Chemistry, Vanderbilt University, Nashville, TN, 2007
                              13. 130. Innovations in Ion Sources for Biological FT-ICR Mass Spectrometry
                                David C. Muddiman
                                6th North American FT-ICR MS Conference, Lake Tahoe, CA, 2007
                              14. 129. Innovations and Applications of the LTQ-FT in the Biological Arena
                                David C. Muddiman
                                ThermoElectron Users Meeting, Lake Tahoe, CA, 2007
                              15. 128. Effectively Addressing Clinical Proteomic Problems using Novel Chemical and Instrumental Approaches
                                David C. Muddiman
                                Department of Pharmaceutics, Virginia Commonwealth University, Richmond, VA, 2007

                      2006Back to top

                              1. 127. Traps, TOF’s and Triples Applied to Global and Targeted Clinical Proteomics
                                David C. Muddiman
                                Divisions of Molecular Pharmaceutics and Medicinal Chemistry, University of North Carolina-Chapel Hill, Chapel Hill, NC, 2006
                              2. 126. Selective Chemistry and Advancing Mass Spectrometry Instrumentation to Effectively Approach Challenging Clinical Questions
                                David C. Muddiman and Adam M. Hawkridge
                                Department of Chemistry, Georgia Institute of Technology, Atlanta, GA, 2006
                              3. 125. Novel Chemical and Instrumental Approaches Coupled to ESI-FT-ICR Mass Spectrometry to Effectively Address Proteomics Questions
                                David C. Muddiman
                                Department of Genome Sciences, University of Washington, Seattle, WA, 2006
                              4. 124. Development of nLC-dualESI-FT-ICR MS and it Applications in Cancer and Cardiovascular Plasma Proteomics
                                David C. Muddiman and Adam M. Hawkridge
                                Federation of Analytical Chemistry and Spectroscopy Societies Lake Buena Vista, FL, 2006
                              5. 123. A Primer and Update on the Current State of Large Molecule Quantification
                                David C. Muddiman
                                Applied Pharmaceutical Analysis, The Boston Society for Advanced Therapeutics, Boston, MA, 2006
                              6. 122. FT-ICR Mass Spectrometry: Putting a High Resolving Power Spin on Protein Identification and Quantification
                                David C. Muddiman, Adam H. Hawkridge, Kenneth L. Johnson, and H. Robert Bergen III
                                231st National American Chemical Society Meeting, Symposium Honoring Richard Caprioli, Recipient of the 2006 Field and Franklin Award, Atlanta, GA, 2006

                      2005Back to top

                              1. 121. Putting a High Resolving Power Spin on Proteomics in the Clinical Domain
                                David C. Muddiman
                                ThermoElectron Proteomics Series, Atlanta, GA, 2005
                              2. 120. Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: Putting a High Resolving Power Spin on Macromolecular Ions
                                David C. Muddiman
                                Department of Chemistry, East Carolina University, Greenville, NC, 2005
                              3. 119. Putting a High Resolving Power Spin on Proteomics in the Clinical Domain
                                David C. Muddiman
                                ThermoElectron Proteomics Series, Rochester, NY, 2005
                              4. 118. Protein Biomarker Discovery: A Tale of Technologies on a Journey Worth Making
                                David C. Muddiman
                                Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 2005
                              5. 117. Protein Biomarker Discovery in Plasma Based on FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Department of Chemistry, University of Georgia, Athens, GA, 2005
                              6. 116. Ovarian Cancer Biomarker Discovery: A Tale of Technologies
                                David C. Muddiman
                                AACR/NCI/EORTC International Conference” Molecular Targets and Cancer Therapeutics: Discovery, Biology and Clinical Applications, Philadelphia, PA, 2005
                              7. 115. Aligning High-End Mass Spectrometry with the Clinical Laboratory: Baby Steps on a Journey Worth Making
                                David C. Muddiman
                                Mass Spectrometry in the Clinical Lab: Matching Technology to Application, American Association for Clinical Chemistry, Orlando, FL, 2005
                              8. 114. Identification and Relative and Absolute Quantification of Proteins using FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Korean Research Institute of Standards and Technology, Taejon, Korea, 2005
                              9. 113. Traps, Triples and TOF’s in the Clinical Domain: Proteomics in the Medical Field
                                David C. Muddiman
                                Seoul University National Hospital, Seoul, Korea, 2005
                              10. 112. Traps, Triples and TOF’s in the Clinical Domain: Proteomics in the Medical Field
                                David C. Muddiman
                                Inje University Sanggye Paik Hospital, Seoul, Korea, 2005
                              11. 111. Implementation of nanoLC-FT-ICR Mass Spectrometry for Studying Circulating Forms of Brain Natriuretic Peptide in Congestive Heart Failure Patients
                                Adam M. Hawkridge, Denise M. Heublein, H. Robert Bergen III, John C. Burnett, Jr., David C. Muddiman
                                North American ICR Meeting, Key West, Florida, 2005
                              12. 110. The Utility of FT-ICR Mass Spectrometry in the Clinical Domain: From Discovery to Targeted Proteomics
                                David C. Muddiman
                                Trapped Ion Meeting, Oxford University, London, England, 2005
                              13. 109. Accurate Characterization of Nucleic Acids by FT-ICR Mass Spectrometry, LGC, Southwestern, England, 2005
                              14. 108. Unraveling the Low Molecular Weight Serum and Plasma Proteome using LC- FT-ICR MS: The Search for Biomarkers Predictive for Early Stage Ovarian and Pancreatic Cancer
                                David C. Muddiman, Adam H. Hawkridge, Kenneth L. Johnson, Ann L. Oberg, Christopher J. Mason, H. Robert Bergen III, William A. Cliby, Janet E. Olson
                                The Association of Biomolecular Resource Facilities, Savannah, GA, 2005
                              15. 107. Development of a Robust Biomarker Discovery Platform Based on LC-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Department of Chemistry, University of Massachusetts-Amherst, 2005
                              16. 106. Protein Marker Discovery in Plasma and Serum: At the Bleeding Edge of Measurement Science
                                David C. Muddiman
                                Department of Chemistry, Oregon State University, Corvallis, Oregon, 2005
                              17. 105. Clinical Proteomics: Making an Impact through the Chemistry Porthole and Building Diverse Research Teams
                                David C. Muddiman
                                Department of Chemistry, Carleton College, Northfield, Minnesota, 2005

                      2004Back to top

                              1. 104. The Challenges and Opportunities of Bringing Proteomics into the Clinical Laboratory
                                David C. Muddiman
                                Endocrine Research Group, St. Mary’s Hospital, Rochester, MN, 2004
                              2. 103. Proteomic Measurements based on FT-ICR Mass Spectrometry: Challenges and Opportunities
                                David C. Muddiman
                                Proteome Society Meeting, London, Ontario, 2004
                              3. 102. Clinical Proteomics: At the Bleeding Edge of Measurement Science
                                David C. Muddiman
                                University of Western Ontario, London, Ontario, 2004
                              4. 101. Mass Spectrometry Based Proteomics: From Discovery to Translation
                                David C. Muddiman
                                Lillehei Heart Institute, University of Minnesota, Minneapolis, MN, 2004
                              5. 100. Targeted and Biomarker Discovery Proteomics using 1D and 2D LC FT-ICR Mass Spectrometry
                                David C. Muddiman
                                3M Corporation, Saint Paul, MN, 2004
                              6. 99. The Role and Impact of 1 and 2D-LC FT-ICR Mass Spectrometry in the Clinical Arena: From Fundamentals to Applications
                                David C. Muddiman
                                Philip Morris, Richmond Virginia, 2004
                              7. 98. Biomarker Discovery in Plasma and Serum: Establishment of a Powerful Platform based on High-Field Magnets
                                David C. Muddiman
                                Manfred W. Comfort Symposium, Radisson Hotel, Rochester, MN, 2004
                              8. 97. Translation of Proteomic Discoveries from the Basic Science to the Clinical Laboratory: The Challenges and Opportunities
                                David C. Muddiman
                                Keynote Speaker, American Motility Society Annual Meeting, 2004
                              9. 96. Biomarker Discovery using a nanoLC-dualESI FT-ICR Mass Spectrometry Platform
                                D.C. Muddiman
                                Protein Biomarkers 2004, Philadelphia, PA, 2004
                              10. 95. An Integrated Biomarker Discovery Platform Based on nanoLC-dual-ESI-FT-ICR Mass Spectrometry
                                A.M. Hawkridge, C.J. Mason, K.L. Johnson, H.R. Bergen, and D.C. Muddiman
                                31st Annual Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Portland, OR, 2004
                              11. 94. Shining a High Resolving Power Spin on Biological Macromolecules
                                D.C. Muddiman
                                Arthur F. Findeis Award Lecture, American Chemical Society, Philadelphia, PA, 2004
                              12. 93. Detection of TTR Variants and Evaluation of siRNA in Mice as a Potential Therapy for Familial Amyloidosis
                                D.C. Muddiman
                                Amyloid Research Group, Mayo Clinic College of Medicine, Rochester, MN, 2004
                              13. 92. The Role of Modern Mass Spectrometry in 21st Century: Fundamental Developments and Emerging Applications
                                D.C. Muddiman
                                Young Mass Spectrometrists, American Society for Mass Spectrometry, Nashville, TN, 2004
                              14. 91. The Classical ER Transcriptional Pathway
                                T .C. Spelsberg, D.G. Monroe, F.J. Secreto, D.C. Muddiman, B.L. Riggs, S. Khosla
                                American Society for Bone and Mineral Research, Bethesda, Maryland, 2004
                              15. 90. Biomarker Discovery using High Performance Mass Spectrometry
                                David C. Muddiman
                                Cambridge Healthtech Institute’s Protein Biomarkers: HighEnd Mass Spectrometry, Philadelphia, PA, 2004.
                              16. 89. The Challenges and Opportunities of Doing Proteomics in a Single Cell
                                David C. Muddiman
                                Cambridge Healthtech Institute’s Eighth Annual Proteomics Meeting. Proteomics: Addressing Challenges in Proteomic Analysis, San Francisco, CA, 2004
                              17. 88. Comprehensive Proteomics: The Integration of High Performance Mass Spectrometry, Genomics and Bioinformatics to Improve Our Understanding of Disease
                                David C. Muddiman
                                J. Craig Venter Science Foundation Joint Technology Center, Rockville, MD, 2004
                              18. 87. Global and Targeted Proteomics using High Performance Mass Spectrometry
                                David C. Muddiman
                                Symposium on Genomic and Proteomic Approaches Toward the Understanding of Drug Addiction, Basic Research Center on Molecular and Cell Biology of Drug Abuse (MCBDA) at the University of Minnesota, Minneapolis, MN, 2004
                              19. 86. Proteomics at the Clinical Interface
                                David C. Muddiman
                                95th Annual Meeting of the Society of Neurological Surgeons, New Orleans, LA, 2004
                              20. 85. High Field LC-ESI FT-ICR Mass Spectrometry: From Gas-Phase Ion Chemistry to Clinical Applications
                                David C. Muddiman
                                Southern Illinois University, Carbondale, IL, 2004
                              21. 84. Biomarker Discovery: High Performance Mass Spectrometry
                                David C. Muddiman and Janet E. Olson
                                Pancreatic Cancer Annual SPORE Retreat, Mayo Clinic College of Medicine, Rochester, MN, 2004
                              22. 83. Protein Characterization in Biological Fluids using High Performance Mass Spectrometry
                                David C. Muddiman
                                St. Olaf College, Northfield, MN, 2004
                              23. 82. Nucleic Acid Analysis Using High Field FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Keystone Symposium on Mass Spectrometry in Systems Biology, Santa Fe, NM, 2004
                              24. 81. Clinical Proteomics by Multidimensional Chromatography Coupled with ESI FT-ICR Mass Spectrometry
                                David C. Muddiman
                                The Pittsburgh Conference (Pittcon 2004), Chicago, IL, 2004
                              25. 80. Development of High Performance Mass Spectrometry to Address Complex Biological Problems
                                David C. Muddiman
                                University of St. Thomas, Minneapolis, MN, 2004
                              26. 79. LC-ESI-FT-ICR Mass Spectrometry: The Ultimate in Peak Capacity and Adaptability for Measuring Biological Molecules
                                David C. Muddiman
                                Department of Chemistry, University of Minnesota, Minneapolis, MN, 2004
                              27. 78. Unraveling Biological Complexity with High Performance Mass Spectrometry
                                David C. Muddiman
                                Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 2004

                      2003Back to top

                              1. 77. MS-Based Proteomics: Instrumentation and Clinical Applications
                                David C. Muddiman
                                Resident Lecture Series, Mayo Clinic College of Medicine, 2003
                              2. 76. Ovarian Cancer Biomarker Discovery using 1D and 2D LC-High Performance Mass Spectrometry
                                David C. Muddiman
                                Ovarian Cancer Research and Clinical Team, Mayo Clinic College of Medicine, 2003
                              3. 75. Targeted and Discovery Proteomics using High Performance Mass Spectrometry
                                David C. Muddiman
                                Clinical Biochemistry and Immunology, Mayo Clinic College of Medicine, 2003
                              4. 74. Clinical Proteomic Applications of LC-ESI-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Associated Regional and University Pathologists, Salt Lake City, Utah, 2003
                              5. 73. Fundamentals and Biological Applications of ESI-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Brigham Young University, Provo, Utah, 2003
                              6. 72. Multidimensional Chromatography ESI-FT-ICR Mass Spectrometry: The Ultimate Peak Capacity for Proteome Measurements
                                David C. Muddiman
                                The 35th Central Regional Meeting of the American Chemical Society, Pittsburgh, PA, 2003
                              7. 71. Beyond Genomics: The Promise of Proteomics
                                David C. Muddiman
                                Genomics in Clinical Practice, Genetic Testing: Past, Present and Future, Mayo School of Continuing Medical Education, Rochester, MN, 2003
                              8. 70. Comprehensive and Rational Ovarian Cancer Biomarker Discovery using High Performance Mass Spectrometry-Based Proteomics
                                David C. Muddiman
                                Women’s Cancer 2003: Merging Science and Care, Mayo Clinic Cancer Center, Rochester, MN, 2003
                              9. 69. Targeted and Global Proteomics by 1D and 2D LC-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                American Society for Bone and Mineral Research Annual Meeting, Minneapolis, MN, 2003
                              10. 68. Clinical Proteomics using One and Two-Dimensional LC Coupled with High Field FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Seminar at Medical College of Wisconsin, Milwaukee, WI, 2003
                              11. 67. Proteomics FT-ICR Style: A Tribute to John Fenn’s Invention
                                David C. Muddiman
                                Mary E. Kapp Lecturer, Virginia Commonwealth University, Richmond, VA, 2003
                              12. 66. Electrospray Ionization Mass Spectrometry of Proteins
                                David C. Muddiman
                                Research Workshop, Wisconsin Symposium III, DNA Conference, Visiting Faculty Member, University of Wisconsin-Madison Medical School, Madison, WI, 2003
                              13. 65. Electrospray Ionization Mass Spectrometry of Nucleic Acids: From DNA: Drug Binding to Genotyping
                                David C. Muddiman
                                Wisconsin Symposium III, DNA Conference, Visiting Faculty Member, University of Wisconsin-Madison Medical School, Madison, WI, 2003
                              14. 64. Comprehensive Proteomics in a Single Cell: Technology and Applications
                                David C. Muddiman
                                Minnesota Chromatography Forum, Minneapolis, MN, 2003
                              15. 63. Genomics and Comprehensive Proteomics in a Single Cell: Technology and Applications
                                David C. Muddiman
                                Eastern Tennessee Mass Spectrometry Discussion Group, Knoxville, TN, 2003
                              16. 62. Characterization of Transthyretin by LC-ESI-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                University of Tennessee at Knoxville, Knoxville, TN, 2003
                              17. 61. Comprehensive Proteomics in a Single Cell
                                David C. Muddiman
                                Mayo Clinic Genetics Society, Mayo Clinic, 2003
                              18. 60. Genomic and Proteomic Measurements in a Single Cell
                                David C. Muddiman
                                4th North American ICR Conference, San Francisco, CA, 2003
                              19. 59. Comprehensive Proteomics Using 2DLC-ESI-FT-ICR
                                David C. Muddiman
                                Seminar at Mayo Clinic Jacksonville, Jacksonville, FL, 2003
                              20. 58. Comprehensive Proteomics in a Single Cell Using HPLC-FT-ICR-MS
                                David C. Muddiman
                                Seminar at 3M Corporation, St. Paul, MN, 2003
                              21. 57. DNA Diagnostics by Mass Spectrometry
                                David C. Muddiman
                                Molecular Genetics Development Meeting, Mayo Clinic, Rochester, MN, 2003
                              22. 56. Accurate, Sensitive and Quantitative Nucleic Acid Analyses by ESI-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                The Cleveland Clinic Educational Foundation, Department of Cell Biology, Visiting Lecture Pro Tempore, Cleveland, OH, 2003
                              23. 55. ESI-FTICR Mass Spectrometry for Genomic and Proteomic Research: From Fundamentals to Clinically Important Applications
                                David C. Muddiman
                                Seminar at the University of California-Riverside, Riverside, CA, 2003
                              24. 54. Genetic Analysis by ESI-FTICR Mass Spectrometry
                                David C. Muddiman
                                Lab Automation 2003, Palm Spring, CA, 2003

                      2002Back to top

                              1. 53. Genomic and Proteomic Characterization by ESI-FT-ICR Mass Spectrometry using IRMPD
                                David C. Muddiman
                                Seminar at the University of Minnesota, Minneapolis, MN, 2002
                              2. 52. ESI-FTICR Mass Spectrometry: From Genotyping to Phosphopeptide Mapping All in a Single Cell
                                David C. Muddiman
                                Seminar at the University of Wisconsin at Madison, Madison, WI, 2002
                              3. 51. Determining Allele Frequency for Single-Nucleotide Polymorphisms by Electrospray Ionization FTICR Mass Spectrometry
                                David C. Muddiman
                                Desorption 2002, Estes Park, CO, 2002
                              4. 50. From SIMS, ESCA and TOF-SIMS to Biological Chemistry: My Herculoid Experience
                                David C. Muddiman
                                Hercules’ Symposium Honoring his 70th Birthday, Nashville, TN, 2002
                              5. 49. Characterization of Biological Molecules by Electrospray Ionization FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Mayo-Karolinska Metabolic & Nutrition Conference, Stockholm, Sweden, 2002
                              6. 48. Accurate, Sensitive and Comprehensive Characterization of Biological Molecules by ESI-FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Delaware Valley Mass Spectrometry Discussion Group, Merck, West Point, PA, 2002
                              7. 47. Mass Spectrometry and Proteomics: Inseparable Partners
                                David C. Muddiman
                                Gannon University and Hamot Medical Center, Erie, PA, 2002
                              8. 46. High Performance Mass Spectrometry for the Study of Biological Complexity
                                David C. Muddiman
                                National Research Council of Canada, Halifax, Nova Scotia 2002 – A Canadian Invention for Canadian Research? (aka “The Great Halifax FTICR Caper”)
                              9. 45. Extensive Evaluation of Novel Sample Preparation Techniques For Using High Sensitivity Mass Measurements of Nucleic Acids Using ESI-FT-ICR Mass Spectrometry
                                Laura T. George (2001-2002 Ingraham Scholar) and David C. Muddiman
                                Richmond Chromatography Discussion Group, Richmond, VA, 2002
                              10. 44. Genomics and Proteomics to Gas-Phase Ion Chemistry: Potential Roles of FTICR Mass Spectrometry in the Post-Genome Era
                                David C. Muddiman
                                Mayo Clinic and Foundation, Rochester, MN, 2002
                              11. 43. Accurate Mass Tag – Isotope Coded Affinity Tag LC-ESI-FTICR-MS for Protein Identification and Quantification
                                David C. Muddiman
                                American Association of Pharmaceutical Scientists, Toronto, CA, 2002
                              12. 42. High Sensitivity and Mass Accuracy of Large Nucleic Acids
                                David C. Muddiman
                                Federation of Analytical Chemistry and Spectroscopy Societies, Providence, RI, 2002
                              13. 41. Genomics to Proteomics: Bridging the Transcriptome with Electrospray Ionization FTICR Mass Spectrometry
                                David C. Muddiman
                                Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, 2002
                              14. 40. Novel, Sensitive and Rapid Approaches for Phosphopeptide Mapping
                                David C. Muddiman
                                Department of Physiology, Medical College of Virginia, Richmond, VA, 2002
                              15. 39. Mass Spectrometric Approaches to Investigate Biological Systems
                                David C. Muddiman
                                Molecular Biology of Cell Growth Meeting, Massey Cancer Center, Medical College of Virginia, Richmond, VA, 2002
                              16. 38. Electrospray Ionization FTICR Mass Spectrometry: A Powerful Platform for a Diverse Range of Post-Genome Applications
                                David C. Muddiman
                                Department of Pharmacology and Toxicology, University of Alabama, Birmingham, AL, 2002
                              17. 37. ‘High Throughput’ Genotyping of Length Polymorphisms by Mass Spectrometry: Forensic and Clinical Applications
                                David C. Muddiman
                                Lab Automation 2002, Palm Springs, CA, 2002

                      2001Back to top

                              1. 36. ESI-FTICR Mass Spectrometry for Genomics and Proteomics Research: From Accurate Mass Determinations for Allele Subtyping to IRMPD for Phosphopeptide Mapping
                                David C. Muddiman
                                Pfizer Global, Ann Arbor, MI, 2001
                              2. 35. Nucleic Acid Analysis by High Performance Mass Spectrometry
                                David C. Muddiman
                                Washington-Baltimore Mass Spectrometry Discussion Group, Gaithersburg, MD, 2001
                              3. 34. Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Macromolecules: Putting a Positive Spin on Negative Ions
                                David C. Muddiman
                                South Eastern Regional Meeting of the American Chemical Society, Savannah, GA, 2001
                              4. 33. Mass Spectrometric Approaches to Stratify Cancer Using Molecular Signatures
                                David C. Muddiman
                                Vanderbilt University, Nashville, TN, 2001
                              5. 32. Mass Spectrometry for the Study of Biocomplexity
                                David C. Muddiman
                                Virginia Commonwealth University Life Sciences Scholars’ Program, Richmond, VA, 2001
                              6. 31. Characterization of Macromolecules by Negative Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
                                David C. Muddiman
                                Eli Lilly, Indianapolis, IN, 2001
                              7. 30. Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for the Analysis of Large Biomolecules: Instrumentation and Applications
                                David C. Muddiman
                                Richmond Chromatography Discussion Group, Whitehall-Robbins, 2001
                              8. 29. Genotyping Short Tandem Repeat Polymorphisms by ESI FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Joint Seminar: Departments of Pharmaceutics and Medicinal Chemistry, Medical College of Virginia, 2001
                              9. 28. Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry with a DNA Twist
                                David C. Muddiman
                                3rd North American FT-ICR MS Conference, Austin, TX, 2001
                              10. 27. Genotyping Short Tandem Repeat Loci Using Accurate Mass Measurements and MS/MS by Electrospray Ionization FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Clemson University, Clemson, South Carolina, 2001
                              11. 26. Genotyping Repetitive DNA Sequences with Non-consensus Alleles and Hypervariablity by Electrospray Ionization FT-ICR Mass Spectrometry
                                David C. Muddiman
                                Case Western Reserve University, Cleveland, Ohio, 2001
                              12. 25. Genomics to Proteomics: Bridging the Transcriptome with Electrospray Ionization FTICR Mass Spectrometry
                                David C. Muddiman
                                Pharmaceutical Congress of the Americas, American Association of Pharmaceutical Scientists, Orlando, FL, 2001

                      2000Back to top

                              1. 24. Electrospray Ionization FT-ICR Mass Spectrometry of Large Biomolecules: Implications of Multiple-Charging for Exact and High Mass Measurements
                                David C. Muddiman
                                Workshop on Biological Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Providence, RI, November 6-7, 2000
                              2. 23. A Novel Algorithm for LC-MS: Enhancements in Both the Signal-to-Noise Ratio and the Resolution of the Analyte Peaks in the Chromatogram
                                David C. Muddiman
                                Chromfare, Richmond, VA, 2000
                              3. 22. Genotyping of Simple and Complex Short Tandem Repeats by Electrospray Ionization Tandem Mass Spectrometry
                                David C. Muddiman
                                Department of Biology, Virginia Commonwealth University, Richmond, VA, 2000

                      1999Back to top

                              1. 21. Genomics to Gas-Phase Ion Chemistry: The Role of Mass Spectrometry in the Post-Genome Era
                                D.C. Muddiman
                                Department of Chemistry and the National High Magnetic Field Laboratory, Florida State University, Tallahassee, Florida, 1999
                              2. 20. Biological Mass Spectrometry: From Small Drugs to DNA
                                David C. Muddiman
                                Department of Chemistry, College of William and Mary, Williamsburg, VA, 1999
                              3. 19. Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: From Subattomoles to Gene Mapping
                                David C. Muddiman
                                Department of Chemistry, Kent State University, Kent, OH, 1999
                              4. 18. Electrospray Ionization Mass Spectrometry: A Powerful and Universal Platform for the Analysis of Genetic Variation
                                David C. Muddiman
                                Department of Chemistry, Louisiana State University, Baton Rouge, LA, 1999
                              5. 17. Investigations of Drug-DNA Interations and Antisense Therapeutics by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
                                David C. Muddiman
                                Massey Cancer Center, Medical College of Virginia, Richmond, VA, 1999
                              6. 16. Electrospray Ionization FT-ICR Mass Spectrometry: A Powerful Platform for Genome and Proteome Characterization
                                David C. Muddiman
                                Atlanta Area Mass Spectrometry Discussion Group, Complex Carbohydrate Research Center, University of Georgia, Athens, GA, 1999
                              7. 15. Quantification of Relative Protein Ion Currents by Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
                                David C. Muddiman
                                Gordon Research Conference on Analytical Chemistry: Microbioanalytical Measurements for the Next Millennium, Henniker, New Hampshire, 1999
                              8. 14. Rapid and Accurate Characterization of STRs, VNTRs, and Drug-DNA Interactions Through the Development of ESI-FTICR Mass Spectrometry
                                David C. Muddiman
                                Functional Genomics: Technology Development and Research Applications, The Banbury Center, Cold Harbor Spring Laboratory, New York, 1999
                              9. 13. Biological Mass Spectrometry: Fundamentals and Applications in Biotechnology
                                David C. Muddiman
                                Hampton University, Hampton, VA, 1999

                      1998Back to top

                              1. 12. Fourier Transform Ion Cyclotron Resonance Mass Spectrometry with a DNA Twist
                                David C. Muddiman
                                Eastern Analytical Symposium, Gold Medal Award Honoring Professor Alan Marshall, 1998
                              2. 11. Unraveling DNA using Electrospray Ionization Mass Spectrometry: A Powerful Platform for Genetic Mutation Screening
                                David C. Muddiman
                                Genome Sequencing and Analysis Conference, The Institute for Genomic Research, Miami Beach, Florida, 1998
                              3. 10. Electrospray Ionization Fourier Transform Mass Spectrometry for Genomic Research
                                David C. Muddiman
                                Merck and Co., West Point, PA, 1998
                              4. 9. High Performance Large Molecule Mass Spectrometry: Instrumentation and Genomics Applications
                                David C. Muddiman
                                Massey Cancer Center, Medical College of Virginia, 1998

                      1997Back to top

                              1. 8. Combining New Analytical Developments with Genomics: A Multi-Disciplinary Approach with a World of Opportunity
                                David C. Muddiman
                                Department of Human Genetics, Medical College of Virginia, 1997

                      1996Back to top

                              1. 7. Electrospray Ionization Mass Spectrometry of Oligonucleotides
                                David C. Muddiman
                                Department of Chemistry and Biochemistry, Montana State University, 1996

                      1995Back to top

                              1. 6. Biological Applications of Mass Spectrometry: I) Investigation of Drugs, Metabolism and Pharmacokinetics II) Sequencing the Human Genome
                                David C. Muddiman
                                Odense University, Department of Molecular Biology, Odense, Denmark, 1995
                              2. 5. Investigation of Oligonucleotides by Electrospray Ionization Mass Spectrometry
                                David C. Muddiman
                                University of Münster, Institute for Medicinal Physics and Biophysics, Münster, Germany, 1995

                      1994Back to top

                              1. 4. Application of Data Analysis Techniques to Time-of-Flight Mass Spectral Data to obtain Quantitative Information
                                David C. Muddiman, A.I. Gusev, A. Proctor, D.M. Hercules
                                Desorption ‘94, Bend, Oregon, 1994

                      1993Back to top

                              1. 3. New Approaches Towards Measurement of Drugs and Metabolites in Microquantities by Time-of-Flight Mass Spectrometry
                                David C. Muddiman, A.I. Gusev, V. Warty, D.M. Hercules
                                Department of Clinical Chemistry, Children’s Hospital, Pittsburgh, PA, 1993
                              2. 2. Time-of-Flight Secondary Ion Mass Spectrometry: Instrumentation and Applications
                                David C. Muddiman, A.G. Sharkey, D.M. Hercules
                                Department of Geology, University of Pittsburgh, Pittsburgh, Pennsylvania, 1993

                      1992Back to top

                          1. 1. Development of New Applications for Time-of-Flight Secondary-Ion Mass Spectrometry
                            David C. Muddiman, D.M. Hercules
                            Aluminum Corporation of America (ALCOA), Pittsburgh, Pennsylvania, 1992